Prof. Dr. Gudrun Brockmann
The regulation of energy expenditure in mammals affects all bodily functions, including metabolic health, reproduction and immune status, and is essential for the efficient utilization of food resources, pollution reduction and animal welfare. Its complex nature is determined by genetics, changes throughout life and is influenced by environmental factors.
The Breeding Biology and Molecular Genetics Group's research covers three areas:
- Investigating genetic variability and identifying gene variants that contribute to differences in energy utilization using structured pedigrees and breeding populations (variables: animal production and welfare traits, body mass and composition, feed efficiency, glucose and lipid consumption, gene expression).
- Investigating causality between sequence variation and phenotypic variation in genetic models.
- Investigating genome structure in selected populations.
To understand the causal molecular changes and overall system regulation of energy homeostasis, they study their own mouse models as well as existing dairy cattle and chicken populations. The Brockmann Group uses a variety of phenotypes, genotypes, and statistical methods to identify genes and sequence variants that underlie variation in traits.
- SNP array
- Whole genome sequencing (including long-range sequencing)
- Genome-wide association studies
- Diversity and inbreeding analyses
- Analysis of evolutionary changes
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