News and Events
-
May the forest be with you!
They are rooting for a better future...
-
Cannabis plants can be high maintenance...
I wish weed make it easer!
-
A stallion's bloodline is fairly STABLE!
But when I told them, they just neighed it off...
-
Spatial SLAM-seq - the slam dunk of RNA Profiling!
I was going to make an RNA joke at first, but I thought it might get lost in translation....
-
One facial expression is worth a thousand words...
The power of non-verbal communication!
-
'All that glisters is not gold'
'Often have you heard that told'...
2023
2024
4D Life Sciences Seminar - Rainer Hedrich
11-12-2024 (Maud-Menten-Saal, Campus Nord)
In his talk ‘Using Ion channel-based optogenetics to study membrane transport and remote controlling plant action and development’ Rainer Hedrich introduced us to the world of plant ion channels, which he has brought about and shaped immensely with his research. Recently, he integrated the fascinating methodology of optogenetics into this field, resulting in numerous interesting findings.
Let a mealworm your heart and your tummy!
The yellow mealworm, Tenebrio molitor, has emerged as a promising sustainable protein source, driving increased interest in its nutrition and growth. However, inconsistencies in experimental protocols have hindered direct comparisons between studies. To address this issue, a standardized protocol has been developed to evaluate the performance of mealworm larvae under various feeding conditions. This protocol provides a framework for researchers to conduct reliable and comparable experiments, facilitating the advancement of mealworm research. The Urban Plant Ecophysiology Group (Christian Ulrichs) participated in an international ring test that assessed the efficacy of the standardized protocol by evaluating the repeatability and reproducibility of the experimental outcomes. Check out their Journal of Insects as Food and Feed Article!
Mastitis is udderly painful!
Mastitis is a common disease in dairy cattle that is often caused by infections of the udder with microorganisms and significantly impacts milk production and quality. While genetic factors have been implicated in mastitis susceptibility, the specific genetic markers associated with different pathogens remain elusive. Previous studies have identified several Single Nucleotide Polymorphisms (SNPs) associated with somatic cell count (SCC), a common indicator of mastitis. The Breeding Biology and Molecular Genetics Group (Gudrun Brockmann) investigated the association between these previously identified SNPs and the presence of three major mastitis pathogens: Escherichia coli, coagulase-negative staphylococci (CNS), and Streptococcus uberis. If you are curious how to use specific SNPs to predict pathogen presence or pathogen resistance, check out their Journal of Animal Breeding and Genetics Article!
Now it's clear as DAE!
NBD-Cl is a fluorescent labeling reagent widely used to track biomolecules such as lipids and proteins or to monitor enzyme activities. However, the potential impact of NBD labeling on cellular metabolism remains a concern. The Optical Nanospectroscopy Group (Janina Kneipp) and the Organic and Bioorganic Chemistry Group (Christoph Arenz) investigated the molecular changes induced by NBD-Cl and NBD-ceramide (NBDCER) in the endolysosomal compartments of 3T3 fibroblast cells and J774 macrophage cells to identify specific molecular alterations and understand their implications for cellular function. Find out more about the 'hidden' contributions of the NBD group in their The Journal of Physical Chemistry C Article!
Not everything in life will go according to plan...
Model-based recursive partitioning has emerged as a powerful technique for identifying subgroups of individuals with distinct patterns of relationships between variables. While traditional approaches have focused on structural equation models (SEMs) for cross-sectional data, recent advancements have extended this methodology to dynamic SEMs for longitudinal data. The Psychological Research Methods Group (Manuel Völkle) has developed a novel approach called score-based CT-SEM trees, which enables the analysis of data with irregular sampling plans. Find out more in their Chapter 'Score-Guided Recursive Partitioning of Continuous-Time Structural Equation Models' in Dependent Data in Social Sciences Research.
Inside every plasmon-catalyzed reaction is the potential for an incredible application!
The conversion and storage of solar (and other form of renewable) energy is a topic that has occupied us for a long time and is only becoming more important with global climate change. Plasmonic catalysis is a method of converting light energy into chemical energy through heterogeneous catalytic reactions induced by plasmons. Together with Zhiyang Zhang, Janina Kneipp delves into the exciting world of plasmon-assisted reactions, focusing on the role of surface-enhanced Raman spectroscopy (SERS) in unraveling their underlying mechanisms. SERS, as a powerful spectroscopic technique, allows for the in-situ observation of molecular interactions at the nanoscale, providing invaluable insights into the key steps of plasmon-catalyzed reactions as well as their potential for application. Check out their Chapter 'Monitoring Plasmon-Assisted Catalysis by SERS' in Surface- and Tip-Enhanced Raman Scattering Spectroscopy!
Heart and soul...
Recurrence Quantification Analysis (RQA) is a powerful technique for analyzing the nonlinear dynamics of time series data. However, traditional RQA is limited to univariate time series. To address this limitation, Multidimensional RQA has been developed to analyze the joint dynamics of multivariate time series. The Social and Organizational Psychology Group (Ursula Hess) and the Psychological Assessment Group (Matthias Ziegler) developed a novel extension of Multidimensional RQA, called Lagged Multidimensional RQA, which allows for the investigation of relationships between different variables within a multivariate time series. Find out more about the utilization of Lagged Multidimensional RQA in analyzing joint action research data, specifically focusing on the shared dynamics between facial expressions and heart rate in their Psychological MethodsArticle!
Time to say goodbye...
Most of us have experienced it at least once in life - a devastating breakup. Romantic breakups can have significant emotional and psychological consequences. While research has consistently shown that men tend to suffer more from these separations than women, the underlying reasons for these gender differences remain unclear. The Developmental and Educational Psychology Group (Denis Gerstorf) investigated the gender-specific responses to romantic breakups, focusing on factors such as initiation of separation, well-being, loneliness, and desire for a new partner. If you are curious about how gender and age affect one's ability to survive a breakup unscathed, check out their Psychology and Aging Article!
Retreat 2024 in Halle an der Saale
We finally went on our first Retreat! Our destination was Halle - a vastly underrated city that is definitely worth a visit! It was a balanced mixture of networking, scientific exchange, future planning and simply fun! Take a look at our report to find out what happened on at the retreat!
Spin there done that...
Spin-orbit interaction plays a crucial role in the behavior of electrons in condensed matter systems. Igor Sokolov investigated the dynamics of spin polarization in a two-dimensional system of spin-1/2 charged particles subject to a perpendicular magnetic field and external noise. If you are curious as well, check out his Physical Review E Article.
You don't need a mood ring. Your face says it all!
Most of us use them in our interactions with other individuals - some more, some less - emotional expressions! Emotion Recognition Accuracy (ERA) is a complex cognitive process influenced by both pattern matching and perspective-taking. The Assessment of Contextualized Emotions (ACE) test is a valuable tool for studying ERA which considers not only the social context and multiple emotions, it simultaneously distinguishes between accuracy (perceiving the intended emotions) and inaccuracy (perceiving additional emotions to those expressed). Using an fMRI-compatible adaptation of ACE the Social and Organizational Psychology Group (Ursula Hess) investigated whether emotion processing is associated with distinct brain activations for single versus group-embedded facial expressions as well as the behavioral relevance of regional changes in activation in the fMRI-compatible ACE task. Find out more about the importance of cognitive bias in the assessment of social emotion perception in their Social Neuroscience Article!
What's better than having a (role) model? Two!
Multivariate decoding techniques are widely used to study the neural basis of working memory. Encoding models offer a promising approach to understanding the tuning properties underlying these neural representations by explicitly modeling the similarity relationships between different stimuli. The Distributed Cognition and Memory Group (Thomas Christophel) set out to evaluate the effectiveness of encoding models for quantifying mnemonic representations using both simulated and real data and found that a reliable identification of the true model requires comparing the variance of two or more competing models. If you want to learn more about this process check out their Journal of Vision Article!
4D Life Sciences Seminar - Serena Ding
13-09-2024 (Maud-Menten-Saal, Campus Nord)
In her talk ‘Collective behaviour of nematodes’ Serena Ding talked about how C. elegans has recently emerged as a model for several striking collective behaviours such as aggregation, wurmuration, and towering. Combining the powerful experimental accessibility of this major lab model organism with the knowledge that collective phenomena are widespread and highly relevant for many nematode species, they use quantitative behavior and behavioral ecology approaches to unravel the mechanism and the function of multiple collective behaviours in ecologically relevant nematode groups.
Are they bugging you?
Aphids are a significant pest of sweet pepper plants, causing damage by feeding on amino acids in the leaves. As magnesium (Mg2+) plays a crucial role in the transport of amino acids from leaves to fruits the Intensive Food Plant Systems Group (Tsu-Wei Chen) investigated whether the application of Mg2+ could reduce aphid colonization by decreasing the availability of amino acids in leaves by promoting their transfer to fruits. If you are curious whether magnesium is the key to improving the nutritional environment for the plant while simultaneously reducing the attractiveness of the leaves to aphids, check out their Scientia Horticulturae Article!
Single Molecule Biophysics Course 2024
09-09 - 13-09-2024 (Biophysics building, Invalidenstr. 42)
The 'Single Molecule Biophysics Course' was a five-day training program designed to eduacte its participants in Single Molecule Theory, Single Channel Recording and Single Molecule Total Internal Reflection Fluorescence (TIRF) Microscopy. It comprised the relevant theoretical background as well as practical sessions to provide a holistic training schedule.
What makes a good drug dealer?
Major Facilitator Superfamily (MFS) proteins play crucial roles in drug transport across cell membranes. In Plasmodium falciparum, the causative agent of malaria, the MFS protein PfMFSDT has been identified as a potential drug transporter. However, its functional relevance in drug resistance remains unclear. By expressing PfMFSDT in C. glabrata - a well-established model organism for studying fungal drug resistance - and analyzing its localization and drug resistance profiles, the Organic and Bioorganic Chemistry Group (Christoph Arenz) has provided important additional information on the role of PfMFSDT in conferring resistance to P. falciparum. Check out their Future Microbiology Article!
I don't believe in confirmation bias!
Confirmation bias - the tendency to favor information that confirms existing beliefs - is a well-documented cognitive bias. While it can lead to irrational decision-making, it has also been shown to improve decision-making under uncertainty. However, the impact of confirmation bias on social decision-making remains relatively unexplored. In order to investigate how confirmation bias influences collective decision-making in a social context the Collective Information Processing Group (Pawel Romanczuk) developed a computational model, which allows to conduct agent-based simulations to explore the effects of resource scarcity, group size, and bias strength on group performance. Find out more in their PLOS Computational Biology Article!
Slowly but surely...
Subdiffusive motion, characterized by slower-than-normal diffusion, is a common phenomenon in various physical systems. In this Physical Review E Review Igor Sokolov and Eugene Postnikov provide an overview about the underlying mechanisms governing subdiffusive motion in constrained environments improving the understanding of how geometric factors influence the dynamics of particles exhibiting anomalous diffusion.
Make the impossible possible!
Sphingolipids are ubiquitous components of membranes in mammalian cells. The most abundant sphingolipid is sphingomyelin the breakdown of which has been associated with the pathogenesis of numerous viral and bacterial pathogens and sphingomyelinases (SMases) have been linked to many widespread diseases such as depression or cardiovascular and neurodegenerative diseases. Since lipids cannot be easily fluorescently labelled as is the case with proteins, their visualization in the cell is rather difficult and as a result their contribution to the infection process is only poorly understood. To overcome this obstacle, the Organic and Bioorganic Chemistry Group (Christoph Arenz) has developed novel trifunctional sphingomyelin derivatives that make it possible to visualize both the distribution and the metabolic activity of sphingomyelin in cells. Find out more about this fantastic innovation in their Nature Communications Article!
Partners in brine!
Group hunting is a widespread strategy among various animal species, offering potential benefits such as increased hunting success and reduced individual risk. Understanding the complex interactions between predators and prey is crucial for comprehending the evolution of cooperation and social behavior. Prey movement plays a pivotal role in predator-prey dynamics. Prey often respond to predation threats by either fleeing or standing their ground, significantly influencing the costs and benefits of predator and prey strategies. The Collective Information Processing Group (Pawel Romanczuk) investigated how prey behavior affects predator strategies of striped marlin, Kajikia audax and the overall dynamics of their predator-prey interactions. Check out their Functional Ecology Article!
Life is short - make the moist of it!
Green infrastructure (GI) plays a crucial role in enhancing urban resilience and sustainability. However, traditional GI planning often overlooks the spatial distribution of residents, leading to potential conflicts between spatial equity and equitable green exposure. The Landscape Ecology Group (Dagmar Haase) established a novel accessibility equity approach for prioritizing GI development in Zhengzhou, China, which considers various socioecological factors and population density and aims to identify areas that require greater focus on GI implementation to ensure equitable access to green spaces and associated benefits. Check out their interesting Sustainable Cities and Society Article!
GUNs don't kill people, they develop plants!
We encounter plants every day (hopefully at least). But have you ever looked at what plants can do at the molecular level? Unlike us, plants have different types of plastids, such as chloroplasts, which use light energy to produce O2 from CO2 and thus provide us with a basis for life on this planet. Plastid biogenesis and the coordination between plastid and nuclear genomes are complex processes and critical for plant development. The protein GENOMES UNCOUPLED1 (GUN1) plays a pivotal role in retrograde signaling, a process that communicates the status of plastid function to the nucleus. Despite extensive research, the molecular function of GUN1 has long remained elusive. However, investigating the function of GUN1 the Molecular Genetics Group (Christian Schmitz-Linneweber) found that the protein is involved in RNA binding and maturation, resolving long-standing controversies about its molecular function. Find out more in their Plant Communications Article!
Oh, for fox sake!
Although city people are less exposed to nature than rural inhabitants, there are numerous points of contact with wildlife in cities. In addition to parks and urban forests, plants and animals that have managed to settle in the city can be found in ordinary streets. Encounters with city animals in particular often leave quite an impression. Who does not remember an unexpected meeting with a fox in the city center, after which one was amazed at how unfazed this creature moves in the midst of crowds of people, cars and skyscrapers? Or the cute little hedgehog that disappeared under the hedge! But I'm sure we all remember the fat rat or racoon that almost gave us a heart attack while taking out the garbage in the evening. The Landscape Ecology Group (Dagmar Haase) investigated how the residents of various German cities perceive their encounters with distinct wild mammals in residential areas by conducting and analyzing an online survey. Check out their interesting Ecology and Society Article!
Why can't mosquitoes suck fat instead of blood?
Lipid droplets (LDs) are essential organelles involved in lipid storage and metabolism. In the malaria parasite Plasmodium falciparum, LDs play a crucial role in the parasite's life cycle. Despite their importance, the specific functions of LDs in P. falciparum remain relatively unexplored. The Molecular Parasitology Group (Kai Matuschewski) investigated the role of LDs in the malaria parasite's lipid metabolism by analyzing their size, composition, and dynamics throughout the parasite's life cycle. You can read more about their valuable insights into the parasite's lipid acquisition and utilization strategies and the potential of LDs as targets for new anti-malarial drugs in their Journal of Cell Science Article!
Our daily dose of air pollution...
Climate change poses significant threats to human health and well-being. Understanding individual vulnerability to climate hazards is crucial for developing effective adaptation strategies. The Developmental and Educational Psychology Group (Denis Gerstorf) established a new intraindividual variability construct, called affective sensitivity to air pollution (ASAP), which measures how an individual's emotional state fluctuates in response to daily changes in air quality. Check out in their PLOS ONE Article to find out more about ASAP and how it can help to incorporate mental health and emotional well-being into climate adaptation strategies to enhance resilience and overall human welfare.
Unlock your (SERS') potential!
Surface-enhanced Raman scattering (SERS) is a powerful technique used to enhance the Raman signal of molecules adsorbed on a metal surface. While traditional SERS focuses on one-photon excited spontaneous Raman scattering, recent advancements have explored nonlinear Raman processes. These processes, driven by high local fields generated by localized surface plasmon resonances (LSPRs), offer unique advantages for studying plasmon-molecule interactions and characterizing nanomaterials. In their ACS Nano Perspective, Janina Kneipp and Katrin Kneipp provide researchers can gain a deeper understanding of plasmon-molecule interactions and explore new applications in materials research, catalysis, and nanobiophotonics.
If I do have a strength, it probably is adaptability...
Plants are able to rapidly adapt to changing environmental conditions. One fundamental adjustment is the expression of chloroplast genes. The essential splicing factor Maturase K has been anticipated to play a generally important role in cholorplast gene regulation, but its importance has so far made it rather difficult to study its function and targets in detail. Together, the Plant Cell and Molecular Biology Group (Kerstin Kaufmann) and the Molecular Genetics Group (Christian Schmitz-Linneweber) investigated which transcripts Maturase K preferably targets and how this translates to a differential expression of functional chloroplast gene groups. Check out their The Plant Journal Article!
Probiotics - eggs-ercise for the immune system?
It is well known, that our gut microbiome has a great influence on our physical and mental wellbeing. Intestinal bacteria help us to break down our food, provide us with vitamins and metabolites and support our immune system. Therefore, a healthy diet and probiotics are powerful tools to modulate our general health. Also chickens are known to benefit from being fed probiotic bacteria, which is assumed to be mainly caused by modulation of the immune system. The Breeding Biology and Molecular Genetics Group (Gudrun Brockmann) investigated how these bacteria interact with the peripheral blood mononuclear cells (PBMCs) of chickens by whole transcriptome profiling and cytokine array analysis. Check out their Frontiers in ImmunologyArticle!
It never get's boaring in the city!
As cities grow and also rural areas are to a large extend characterized by agriculture and infrastructure natural habitats for wildlife are becoming increasingly scarce. Oganisms that are able to adapt to urban conditions however can profit from the these can benefit from the diverse supply of food and shelters attracting more wildlife to the cities. This coexistence can lead to conflicts. In order to better understand which animals have a high potential for conflict and how these conflicts can best be resolved, the Landscape Ecology Group (Dagmar Haase) interviewed experts and summarized their findings in their People and Nature Article! You should definitely check it out!
Does a joke become a dad joke when it becomes apparent?
Developmental psychology investigates human growth and changes across the lifespan. This comprises the physical, cognitive, social, intellectual, perceptual, personality and emotional development. The developmental cascade model describes how the speed to process information increases with age (especially in our early years), which boosts the working memory, which in turn improves fluid intelligence. While these factors naturally vary from person to person also a intra-subject variability exists. The Psychological Research Methods Group (Manuel Völkle) investigated the role of intra-subject variability within the pathways that constitute the developmental cascade model. Check out their Intelligence Article!
4D Life Sciences Seminar - Moritz Helmstaedter
10-07-2024 (Seminarraum 1'306 - Schrödinger Center, Campus Adlershof)
In his talk 'Cerebral Cortex Connectomics' Moritz Helmstaedter spoke about the mapping of neuronal connectivity, which is one of the main challenges in neuroscience. Only with the knowledge of wiring diagrams is it possible to understand the computational capacities of neuronal networks, both in the sensory periphery, and especially in the mammalian cerebral cortex. The methods of the Department of Connectomics for dense circuit mapping are based on 3-dimensional electron microscopy (EM) imaging of tissue, which allows imaging nerve tissue at nanometer-scale resolution across substantial volumes, extending to more than one millimeter on the side, followed by AI-based image analysis to obtain dense connectivity maps, or connectomes. With these they have mapped local circuitry in mouse and human cortex, determining learning-related synaptic traces, inhibitory axonal development, and discovering an expanded interneuron-to-interneuron network in the human cortex. Most recently they completed the connectomic reconstruction of a cortical column. They are currently screening cortical connectomes across age, disease states and experience to obtain a deeper understanding of their relevance for individual behavioral performance and brain pathology.
I always tern up for birdwatching!
While some predators compete with each other for prey, others benefit from the other, intentionally or unintentionally. Seabirds, for example, profit immensely from the presence of subsurface predators and therefore often share a habitat. However, the principle behind this phenomenon is poorly understood. The Collective Information Processing Group (Pawel Romanczuk) performed spatio-temporal analysis of drone footage to unravel the hunting behaviour of Indo-Pacific sailfish and terns and made some interesting discoveries. Find out more in their Biology Letters Aritcle!
Can you make fish farming more e-fish-ient?
We live in a world in which resources are becoming increasingly scarce while the waste we produce has taken on immense dimensions. For this reason, sustainability is a necessary key issue in various areas of business, science and politics. The circular bioeconomy concept is a new economic model that emphasizes the use of renewable and natural ressources and the minimization of waste production, and thus attempts to meet the sustainability challenges and social demands of our society in equal measure. One important aspect is the promotion of biological production cycles, which involve the introduction products or wastes from one production system to another, thereby optimizing the yield of the resources used. The Urban Plant Ecophysiology Group (Christian Ulrichs) investigated which food source resulted in the highest biomass gain of the fish species Nile tilapia to optimize resource utilization. Check our their Frontiers in Sustainable Food Systems Article!
Welcome to GreenCityLabHuế
The GreenCityLabHuế project aims to strengthen the climate resilience of Huế, Vietnam, through nature-based solutions (NBS) for heat adaptation and air quality improvement. The project will create a multidisciplinary research space to develop and test NBS, focusing on green-blue infrastructure (GBI) and generate knowledge for stakeholders and decision-makers on NBS, resulting in a city-wide vision for sustainable urban development. In their Land-use change and nature-based solutions impact assessment the Landscape Ecology Group (Dagmar Haase) assesses the potential impacts of GBI interventions on ecosystem service supply and demand in Huế and estimate the benefits of GBI for air quality regulation and green space availability.
What is your opinion on beavers?
Not so long ago, beavers were threatened with extinction in Germany. The good news is that the German beaver population has grown considerably and is no longer considered an endangered species. The bad news is that we humans don't like it at all when someone else drastically and effectively changes the environment, especially if it is to our disadvantage. The Landscape Ecology Group (Dagmar Haase) has studied the competition in detail and analyzed where conflicts of interest arise between humans and beavers and discussed approaches that would enable a mutually acceptable coexistence. Have a look at their People and Nature Article!
Don't shoot the messenger (RNA)!
Messenger RNA (mRNA) are molecules in cells that carry the genetic information from the DNA in the nucleus to specific cytes in the cytoplasm where their protein synthesis takes place. To this day it is not entirely clear how mRNA localization is regulated. One widely accepted mechanism is the regulation via localization sequences within the mRNA interacting RNA-binding proteins, however only few examples have been identified so far. In her nature cell biology Review, Marina Chekulaevasummarizes the existing knowledge from the literature to convey a holistic understanding of this fundamental process and potential underlying mechanisms.
Let's focus on the good!
The mood of the people around us can be contagious - both in a positive and negative sense. Cortisol, a hormone that is released in response to stress and low blood sugar levels, induces the increase of the glucose concentration in the blood, down-regulates the immune system and promotes the turnover of calories. Since the release of cortisol is connected to emotional experiences, one might think that it can therefore also be influenced by the emotional states in our environment, especially by those close to us. The Developmental and Educational Psychology Group (Denis Gerstorf) investigated if and how a person’s emotions influence the partner’s cortisol state and interestingly found that positive rather than negative emotions impact one’s partner on cortisol level. Find out more in their Psychoneuroendocrinology Article!
Instant Ram∉an Spectroscopy
Raman spectroscopy is a powerful and versatile technique that allows the examination of materials, biological and forensic samples without the requirement of fixation or sectioning and even enables the analsis of very small volumes. In this tutorial review, Janina Kneipp summarized the basics and influential factors that should be taken into account to successfully obtain Surface Enhanced Raman Scattering (SERS) spectra. If you want to get familiar with or enhance your knowledge of this technique check out their Chemical Society Reviews Review!
The Biophilia Effect
Nowadays, we live in a world that is increasingly moving away from rural life towards urban life. The urban world we have created has a strong impact on our environment and also has a significant influence on our health and social life. But how will our cities look like in the future? It should be our concern to create a habitat in cities where both humans and diverse wildlife can coexist. The Landscape Ecology Group (Dagmar Haase) reviewed existing literature of wild mammals in urban areas to investigate how urban areas should be managed and shaped to achieve coexistence of humans and wild mammals. They identified shortcomings in the existing literature and defined five key elements for a research agenda. Check out their Basic and Applied Ecology Research paper.
It's always a good idea to keep an ion your electrons!
Plasmonics is a field of study that explores the interaction between electromagnetic fields and free electrons in a metal. When light interacts with the surface of a metal at a specific frequency, it can excite collective oscillations of the metal's free electrons, known as plasmons. These plasmons can be confined to very small dimensions, much smaller than the wavelength of light, enabling the manipulation of light at the nanoscale. This characteristic has led to the application of surface plasmon resonance in a variety of areas such as surface-enhanced Raman scattering (SERS), metal-enhanced fluorescence (MEF), photocatalysis, optical trapping or heating. The Optical Nanospectroscopy Group (Janina Kneipp) has developed a method for a simple and low-cost preparation of functionalized nanoporous metal films decorated with rhodium nanoparticles, which can be exploited as plasmonic materials for enhanced UV Raman spectroscopy. If you want to learn more about their preparation and application check out their Materials Advances Article!
I don't like stress because stress stresses me out!
Stress is a natural human response that is triggered when we are under pressure or feel/are threatened. In our modern society stress appears to be a constant companion causing all kinds of stress-related disorders including depression and anxiety. This makes measures that promote our mental and physical well-being all the more important. The Psychological Research Methods Group (Manuel Völkle) compared the effectiveness of two online contemplative mental training programs and found that daily socio-emotional dyadic practices appear to represent a capable approach for stress reduction. Find out more in their Frontiers in Endocrinology Article!
2024 Annual Meeting of the Organization for Human Brain Mapping (OHBM) in Seoul, South Korea
Travel Grant Report from Alina Podschun
Alina Podschun from the Molecular Psychology Group (Sebastian Markett) received an IZ LIST Travel Grant to visit the 2024 Annual Meeting of the Organization for Human Brain Mapping (OHBM) in Seoul, South Korea and was kind enough to share with us what she experienced and what she has taken away from this trip.
In summer, my favorite outdoor activity is going back inside...
People living in bigger cities are most likely familiar with the urban heat island (UHI) effect, meaning that urban areas tend to be considerably warmer than the surrounding rural areas. To better understand the underlying factors the Landscape Ecology Group (Dagmar Haase) investigated how city composition, layout and landscape patterns impact the land surface temperature (LST) in the Megacity Lahore, Pakistan. If you are interested how to create healthier and more comfortable environments in cities check out their Environmental Monitoring and Assessment Article!
4D Life Sciences Seminar - Masazumi Fujiwara
13-06-2024 (Maud-Menten-Saal, Campus Nord)
In his talk 'Nanodiamond quantum thermometers and their applications in biology' Masazumi Fujiwara introduced fluorescent nanodiamonds, which are stable and nontoxic fluorescent probes that are suited to chemical and biological analysis. Recently, they have been intensively studied for quantum applications because their electron-spin-dependent fluorescence can provide a sensitive measurement tool for nanoscale information of magnetic field and temperature. In his talk, Masazumi Fujiwara sproke about his group's effort on the implementation of this technology to temperature measurements in biological analysis (Fujiwara et al., 2020, Oshimi et al., 2022) with some recent results on their novel nanodiamonds (Oshimi et al., arXiv). Furthermore, he discussed potential applications of this technology.
If my mouth doesn't say it, may face definitely will...
The facial expression of emotions is important in regulating social interactions in everyday life. However, like any social signal, the perception of facial expressions, is influenced by contextual information such as body posture, the person’s physical environment, the voice or background knowledge about the person. The Social and Organizational Psychology Group (Ursula Hess) investigated whether expansive valence or rather specific emotion matches are responsible for providing context and how multiple sources of contextual information influence emotion recognition. Check out their Emotion Article!
You make me sick!
Bacteria make up just over half of our cells and live in or on our tissues and body fluids. Many of these tiny organisms perform essential tasks for us such as the fermentation of food, the protection against pathogens, the stimulation of our immune response as well as the production of vitamins. Representatives of the species Klebsiella oxytoca are an important part of the human microbiome, especially in the first years of our lives. Curiously enough, they are able to produce dangerous toxins, but still contribute significantly to the protection against colonization by exogenous microorganisms. The Molecular Microbiology Group (Marc Erhardt) investigated this phenomenon, which at first glance seems contradictory, in order to better understand the intermicrobial interactions. Have a look at their Nature Microbiology Article!
Chloroquine on steroids! What could go wrong?
Malaria is a mosquito-transmitted life-threatening disease that is caused by the parasitic eukaryote plasmodium falciparum. Like most parasites, P. falciparum is dependent on the supply of nutrients from the host. One compound the organism is not able to sythesize itself is the lipid cholesterol. The Molecular Parasitology Group (Kai Matuschewski) investigated whether antimalarial drugs conjugated to cholesterol-analogous compounds show an antimalarial effect, which could provide a significantly improved drug efficiency. Find out more in their EMBO Molecular Medicine Article!
You're Only as Old as You Feel...
You probably heard the saying 'It's downhill after you turn 30' and it actually seems as if the aches and pains increase from this age. Your back troubles you here, your knee hurts there and those headaches! The Developmental and Educational Psychology Group (Denis Gerstorf) investigated the connections between pain, subjective age, and chronological age in middle-aged and older adults and found indications that one's subjective age may act as a predecessor as well as a consequence of pain, which in turn can result in a faster increase in subjective age. Check out this interesting Psychology and Aging Article!
Trees - they're all bark and no bite...
You may have noticed that some trees in the city have been suffering from the unusually high temperatures and low rainfall in recent years. A healthy urban vegetation is not only important to counteract the increasingly rising temperatures, but they also improve air quality, buffer noice, and provide a space for recreation. Thus, monitoring the effects of drought on vegetation is crucial. The Landscape Ecology Group (Dagmar Haase) has established a new workflow that uses freely available remote sensing imagery from Sentinel-2 to holistically monitor urban green spaces providing an important foundation for future research and green space management. Find out more in their Ecological Informatics Article!
Tyrosine Rex - The king of axonal transport...
A functioning axonal transport is essential for nerve development, function and survival, as it involves the delivery of diverse cargoes from one end of the axon to the other. This process is carried out by motor proteins, which move the cargo along the microtubule cytoskeleton. The Optobiology Group (Marina Mikhaylova) investigated the importance of tyrosination and detyrosination of microtubules for functional axonal tranport. Check out their Journal of Cell Science Article!
When the 'rich club' is taking everything from you...
Alzheimer’s disease (AD) is a neurodegenerative disorder that is associated with a progressing decline in cognitive function. In the majority of cases, symptoms like the deterioration of memory and thinking skills appear at an advanced age. The 'rich club' describes highly connected network hubs, whose involvement in the development of AD is not clear at the moment. The Molecular Psychology Group (Sebastian Markett) was able to demonstrate first connections between AD and the rich club. You should definitely check our their Research Report published in Wiley!
How many arthropods have you rescued today?
Most people will probably have heard that the human-induced insect extinction is a major problem for the future of our planet as a habitat, as they perform fundamental functions such as pollinators or natural defense against pests. Insects, which belong to the Phylum of artropods are not the only creatures of this group that perform essential tasks. Even though creatures like spiders, scorpions, millipedes and centipedes are often disliked or even feared, they make important contributions to the biodiversity of ecosystems, breaking down decaying plant materials and control insect population sizes. The Urban Plant Ecophysiology Group (Christian Ulrichs) investigated the effect of different winter wheat cultivation systems on the biomass and abundance of arthopods. Check out their Environmental Monitoring and Assessment Article!
As a 'cityzen' I find trees quite shady!
City folk in particular often have an ambivalent relationship with trees. They beautify the cityscape, clean the air and provide us with oxygen, hold the soil together and protect it from erosion, the list goes on... On the other hand, the nasty trees rob us of our space to build buildings and roads and I'm pretty sure their chosen method of reproduction via pollen is simply to wipe out not just allergy sufferers but all of humanity. The Landscape Ecology Group (Dagmar Haase) addressed this topic in their Urban Ecosystems Article, which you should check out if you are interested in the future of humanity.
Did you hear the joke about mosquitoes?
Malaria is a disease transmitted by mosquitoes that affects different kinds of vertebrates. Although the life cycle of the malaria-causing plasmodia - besides the mosquito - typically involves only one preferred type of vertebrate, there are regular infections of humans with non-human pathogens and vice versa. To better understand the evolution and diversity of malaria parasites the Molecular Parasitology Group (Kai Matuschewski) investigated Plasmodium infections in bats and was able to identify a new species. Check out their International Journal for Parasitology Article!
4D Life Sciences Seminar - Fabian Voigt
16-05-2024 (BIMSB Lecture Hall, Campus Nord)
Seeing is believing and thus, optical imaging techniques are extremely useful to study brain structure and function. In his talk 'Expanding the bag of optical tricks for neuroscience' Fabian Voigt talked about three projects aimed at providing the neuroscience community with better imaging instrumentation: These range from open-source light-sheet microscopes for imaging cleared tissue (mesoSPIM); novel multi-immersion microscope objectives that take inspiration from scallops and astronomical telescopes; and establishing event-based vision as an imaging modality that allows high-speed recordings of physiology and behavior over long time periods without generating overly large datasets.
Research stay in the laboratory of Michael Sattler at the Technische Universität München (TUM) in Munich
Travel Grant Report from Frederick Saulich
We were happy to be able to support Frederick Saulich during his research stay the the Sattler Lab at the TUM in Munich and were excited to read his experience report.
What doesn't kill you makes you stronger!
Plants like Arabidopsis thaliana can withstand a wide range of temperatures and can also tolerate large temperature fluctuations. This ability demands a high degree of flexibility from the plant, which is provided at the molecular level, among others, by phase separation. This phenomenon enables the formation of membrane-less compartments, which represent a dynamic and flexible alternative to organelles, as they can be rapidly modulated by changes in protein concentrations, metabolites, salt or temperature. The Molecular Genetics Group (Christian Schmitz-Linneweber) investigated the role of the protein CP29A in the adaptation to changing temperature conditions and found that the protein undergoes temperature-dependent phase separation thereby regulating the expression genes involved in adaptation to cold climate. Check out their The Plant Cell Article!
Whoever says 'GenBank' and 'UniProt' must also say 'MicrobioRaman'!
Biological databases are valuable tools that provide information about the structure of biomolecules and their interactions, and help to analyze, explain and manipulate biological phenomena and to understand the evolution of specific traits and entire species. The Optical Nanospectroscopy Group (Janina Kneipp) participated in a joint effort to set up a new freely accessible archive for microbiological Raman spectroscopy data. If you want to know more about ‘MicrobioRaman’, check out their Nature Microbiology Article or the database itself!
7th Insi(ght)de LIST Seminar (2024)
Teamwork makes the dream work...
Complex collective behaviors of human, animal and even robotic collectives are the result of the interplay of individual dynamics and social interactions. To understand how individuals that are part of groups make use of social information e.g. during foraging together, and how this application of social information impacts the collective outcome through the behavior of single individuals, the Collective Information Processing Group (Pawel Romanczuk) developed a model that combines models of individual decision-making of foraging agents (evidence accumulation processes) with the movement models of these individuals in space. If you want to find out more and how this model paves the way for fully decentralized mobile robot applications, check out their PLoS Computional Biology Article!
Lonely is not being alone, it's the feeling that no one cares...
The COVID-19 pandemic has impacted the mental and physical well-being of individuals across all age groups, but it's anticipated to have particularly prolonged and pronounced effects on younger populations. As loneliness has been linked to an increased risk of mental health problems such as depression, anxiety, and suicidal ideation as well as cardiovascular and cognitive issues, this should be considered a very serious matter. The Psychological Research Methods Group (Manuel Völkle) compared the effects of an app-based classic mindfulness training program and an innovative partner-based socio-emotional practice (Affect Dyad). Not surprisingly, the partner-based training program was more effective. You can find out more in their International Journal of Environmental Research and Public Health Article!
6th Insi(ght)de LIST Seminar (2024)
Rather CTD than STD ^^
The C-terminal domain (CTD) of the RNA polymerase II serves as a flexible binding scaffold for numerous nuclear factors, which is controlled by its phosphorylation status. The CTD is important for the initiation of DNA transcription, mRNA capping and the association of the spliceosome with the transcript for mRNA splicing. Although phospho-specific antibodies are commonly used to detect CTD phosphorylation patterns, their recognition repertoire has barely been explored due to the challenging synthesis of long multiphosphorylated peptides. The Bioorganic Synthesis Group (Oliver Seitz) set out to develop a method that provides simple and reliable access to multiphosphorylated CTD peptides of up to 12 heptad repeats (84 amino acids) in length. Find out more in their Journal of the American Chemical Society Article!
Where do you go, my lovely?
These days, everyone carries a tracker around with their cell phone. What on the one hand is a somewhat creepy thought can in some situations not only be convenient, but a real lifesaver. Real-Time Location Systems (RTLS) can also be used in the livestock farming world. Obtaining information about the time animals spend in relevant functional areas (e.g feeder) or elimination areas as well as its activity could deliver valuable information about the animal's general well-being and social behavior. The Animal Husbandry and Ethology Group (Lorenz Gygax and Edna Hillmann) tested the commercial Noldus Information Technology BV TrackLab system to validate its accuracy, precision, and data quality and also its suitability to monitor fattening pigs. Read more in their Animal Article!
Damn it's cold outside!
The exposure of plants to cold temperatures induces a process called cold acclimation, where gene expression is significantly altered to allow the plant to adapt to their new environmental conditions. The Plant Cell and Molecular Biology Group (Kerstin Kaufmann) investigated the role of the repressive histone 3 lysine 27 trimethylation in this process to better understand the involvement of chromatin regulation. Find out more in their Frontiers in Plant Science Article!
5th Insi(ght)de LIST Seminar (2024)
12-04-2024 (Erwin Schrödinger Center, Seminar room 1'308, Campus Adlershof)
- Ursula Hess (Psychology)
- Dagmar Haase (Geography)
- Janina Kneipp (Chemistry)
I am not schizophrenic!
Schizophrenia is a mental disorder that is predominantly characterized by recurring psychotic episodes and can be associated with other symptoms such as hallucinations (e.g. hearing voices), delusions (e.g. paranoia), disorganized thinking or social withdrawal. Many people associate the label 'schizophrenia' with negative and often false beliefs and consequently the concerned individuals often face a negative perception and treatment. The Social and Organizational Psychology Group (Ursula Hess) investigated how the label 'schizophrenia' affects liking, interpersonal closeness, and emotional mimicry, to assess what this tenacious stigma is based on. Find out more in their Cognition and Emotion Article!
It's not a diet, it's a lifestyle change!
The COVID-19 pandemic caused until then unprecedented changes in people's lifestyle, work and social interactions. Social distancing and the closing of gathering and interaction centers such as parks, cafes, educational institutions etc., entailed certain social, mental and physical health circumstances. One predominant factor was unintentional changes in body weight, which have been reported for younger and middle-aged adults. As the affect on older adults was hardly considered, the Developmental and Educational Psychology Group (Denis Gerstorf) investigated this particular age group in the course of the pandemic. Find out more in their The Journal of nutrition, health and aging Article!
Why you should 'let the sow out'!
Sows spend most of their time lying down, and their lying behavior and, in return also, their activity level appear to be indicators of their welfare, as they reflect their ability to meet their physical and behavioral needs for rest or movement, which is especially important during parturition and lactation. The Animal Husbandry and Ethology Group (Lorenz Gygax and Edna Hillmann) investigated lying behavior of crated and free farrowing sows to compare how the distinct housing systems allow them to fulfill their needs for rest or movement and to evaluate the accuracy of accelerometer-based sow lying behavior classification. Check out their Journal of Animal Science Article!
To dye or not to dye...
Fluorescence molecular rotors (FMRs) are a group of fluorescent molecules that undergo an intramolecular twisting motion, which non-radiatively depletes the excited state. As a result, environments that prevent this twisting motion, produce enhanced fluorescence. In the past, these dyes have been used mainly to measure nanoviscosity or interactions of FMR-labelled ligands with proteins and nucleic acids. The Bioorganic Synthesis Group (Oliver Seitz) explored covalent labelling of cell surface sialic acids with the FMRs and established the application of FMR dyes to detect interactions with glycans, expanding the use of FMRs. Find out more in their Chemical Communications Article!
Nature is not a place to visit, it is home.
Cultural ecosystem services (CES) and disservices are the positive or negative contributions that ecosystems make to human well-being. This refers to a person's identity, experiences and capabilities that are generated by interaction with environmental spaces, human perception and activity undertaken in this space. The Landscape Ecology Group (Dagmar Haase) examined how the advantages and disadvantages of CES occur together, and explored the connection between spatial and landscape features and the specific benefits and drawbacks associated with them. Find out more in their Science of The Total Environment Article!
Data makes the world go round!
Modelling biological systems is a significant and increasingly important task that involves the use of computer simulations of biological systems in order to analyze and visualize the underlying complex connections. To obtain precise models high quality data is a prerequisite. The Theoretical Biophysics Group (Edda Klipp) reviewed basic requirements to data for whole-cell models and strategies how to combine them. Check out their FEMS Yeast Research Article!
Long live the Bell state!
Semiconducting quantum dots (QDs) hold significant potential for scalable quantum information processing as the localized electrons and spins can be used as qubits, a two-state quantum-mechanical system. In coupled QDs, the electrons can be entangled, which means that the quantum state of one particle cannot be described independently of the state of the other. The simplest example of two qubits’ quantum entanglement are the Bell sates, a form of entangled and normalized basis vectors. The Statistical Physics and Nonlinear Dynamics Group (Igor Sokolov) investigated the stability of different two-qubit entangled Bell states in coupled QDs in the presence of fluctuations. If you are curious what they found out, check out their recent publication in Physical Review!
Green is cool!
Summer in Berlin feels so much hotter and more suffocating than it does on the countryside, especially during the night, when temperatures just won't drop. To counteract the urban heat island effect, particularly as temperatures will only rise in the upcoming years, the expansion of green spaces (GS), which have a cooling effect, is a prerequisite for for living in cities in the future. The Landscape Ecology Group (Dagmar Haase) investigated, the relationship between GS and land surface temperature using the Chinese megacity Guangzhou as an example and found that a combination of increasing the area and optimizing the spatial distribution of green spaces results in the best cooling effects. Find out more in their Environmental Science & Technology Article!
Lonely, I'm so lonely...
Loneliness has been identified as a significant global public health issue and is associated with an increased risk for depression, compromised immunity, chronic illness, and even mortality. The Developmental and Educational Psychology Group (Denis Gerstorf) investigated the historical development of loneliness through midlife and compared how different factors, such as cultural norms, economic inequalities and policy frameworks relating to employment, family dynamics and healthcare affect these changes in the United States and in different countries across Europe. Find out more in their American Psychologist Article!
Mosquitoes suck...
In postmortem human brains, sequestration of infected red blood cells (iRBCs) in the small blood vessels of the brain is a distinctive feature of cerebral malaria (CM). As there's ongoing debate regarding how this phenomenon contributes to the manifestation of the disease, especially the development of fatal brain swellings, the Molecular Parasitology Group (Kai Matuschewski) investigated iRBC-triggered inflammation and its affect on the blood flow in the brain. Find out more in their Nature Communications Article!
What makes a breadwinner?
Meeting the food needs of an ever-growing world population is one of the great challenges of the future. Bread wheat (Triticum aestivum L.) is an essential agricultural product, that plays a critical role in meeting human dietary needs and sustaining energy requirements. As spike architecture influences size and number of grains and consequently grain yield, the Plant Cell and Molecular Biology Group (Kerstin Kaufmann) have tackled the important task of dissecting the genetic and molecular basis of spike traits. Find out more in their Plant Communications Article!
Imaging is good, but optogenetic control is better!
Single-molecule fluorescence microscopy is a powerful technique that has helped to elucidate the function and interplay of actors in numerous essential cellular processes such as the stepping of motor molecules, DNA replication, transcription, translation, or membrane receptor activity. By combining single-molecule fluorescence microscopy with the use of PhoCl, a recently developed green-to-red photo-convertible protein, the Cellular Biophysics Group (Andrew Plested) was able to establish a new experimental paradigm that allows for quantitative, single-molecule imaging as well as optogenetic control over membrane protein function. Check out their Nature Methods Article!
All you need is green...
Green spaces (GS) are vital for improving human well-being as they not only provide environmental regulation services but also cultural amenities. Urbanization has led to an insufficient provision of urban GS along with an uneven distribution, posing significant risks to human health and environmental equity. The Landscape Ecology Group (Dagmar Haase) investigated, the equity of GS availability between urban villages and residential quarters, which are two common residential neighborhood types in Chinese cities. Find out more about the differences and their effects in this Journal of Cleaner Production Article!
Hold on, let me overthink this!
We are affected by everyday stressors in very different ways, which has been linked with differences in our personality. Especially the tendency to overthink appears to increase the negative perception of seemingly everyday situations. The Developmental and Educational Psychology Group (Denis Gerstorf) investigated how other character traits, such as extraversion and openness, affect our psychological and emotional perception of our surroundings and events that we experience on a daily basis. Read more in their Journal of Research in Personality Article!
Are you mentally mapping?
In the field of behavioral geography, a mental map refers to an individual's subjective perception of their environment and interactions within it. The Landscape Ecology Group (Dagmar Haase) investigated how sub-urban Stockholm citizens perceive the green-blue infrastructure (GBI) in their surroundings. You can find out more about mental mapping in their Urban Forestry & Urban Greening Article. How aware are you of your environment and how would such a map look like for your home and work surroundings?
4th Insi(ght)de LIST Seminar (2024)
23-02-2024 (Maud-Menten-Saal, Campus Nord)
- Kerstin Kaufmann (Biology)
- Denis Gerstorf (Psychology)
'TikTok' - 'Who's there?'
TikTok, is a popular short-form video hosting service from China that is among the fastest growing infotech brands, resulting in an increasing cultural impact worldwide. Numerous countries have implemented restrictions, bans, or endeavors to prohibit the usage of TikTok, among others, due to apprehensions over the presence of toxic content, dissemination of misinformation, and potential negative implications for mental health.
Sebastian Markett investigated factors that are associated with extensive TikTok Use and could identify a neurotic or conscious personality to be connected with a higher tendency toward TikTok Use Disorder (TTUD). Find out more in his BMC Psychology Article!
The potential double life of an sRNA...
Apicomplexa are a diverse group of unicellular parasitic eukaryotes whose primordial mitochondrial genomes comprise 30 – 40 genes encoding for small RNAs (sRNAs) of which numerous resemble E. coli rRNA. The Molecular Genetics Group (Christian Schmitz-Linneweber) investigated the expression and function of these sRNAs and their findings provided first hints for a dual utilization of mitochondrial sequences as messenger RNAs as well ribosomal RNAs. If you are interested in these seemingly moonlighting sRNAs, check out their eLife Article.
Can you imagine?
Visual imagery is our capacity to revive and manipulate visual depictions even when the corresponding visual stimuli are not present. The Distributed Cognition and Memory Group (Thomas Christophel) investigated how the vividness of visual imagery affects the strength of visual working memory representations in the visual cortex by comparing the ability of strong imagers to retain information about a stimulus feature compared to weak imagers. Have a look at their Wiley Article to find out more!
Guest Talk - Hiroshi Mamitsuka
13-02-2024 (Large Seminar room, Invalidenstr. 42 - Mittelbau)
In his talk 'Machine learning for multiomics data: realizing precise drug response prediction' Hiroshi Mamitsuka explained how Bayesian Data IntegratiVE Learning for Precise Drug ResponSE Prediction (DIVERSE) can be used to predict biomarkers from multiomics data. Biomarkers serve as essential tools for the diagnostics of complex diseases and improve the treatment of patients.
It may look like I'm doing nothing, but I'm actually evolving!
Dormancy is a temporary and reversible slowdown or suspension of an organism's regular physical functions. This state is a ubiquitous trait in microbial communities, but can also be found in complex organisms including animals and plants. The Interdisciplinary Mathematics Group (Maite Wilke Berenguer) investigated the impact of dormancy on evolutionary branching and found that this seemingly passive state has a significant influence on the development of populations with new traits and, as a consequence, diversity. Check out their Theoretical Population Biology Article.
Your plants won't leaf you!
Unlike animals, terrestrial plants are unable to move from one place to another. Thus, they depend on adapting to their environment for instance by adjusting their height, root growth or photosynthetic capacity. The Plant Cell and Molecular Biology Group (Kerstin Kaufmann) investigated how Arabidopsis adapts its gene expression, and as a result several important pathways, in response to different light conditions. Find out more in their BMC Plant Biology Article!
How to feed a catfish...
To meet the growing global demand for nutritious aquatic foods, it is imperative to embrace sustainable aquaculture practices and technologies. In this study Christian Ulrichs investigated the impact of gradually replacing animal proteins with plant proteins in the diets of African catfish in aquaponic systems. The study further highlights the importance of balanced protein sources for optimal aquaponic system performance and provides insights into nutrient dynamics in recirculating aquaculture systems.
Do you want to pick your brain a little?
Our sensory working memory allows us to temporarily hold onto what we see, hear, or feel, facilitating mental processes like thinking, problem-solving, and understanding even when the sensory input is no longer available. The Distributed Cognition and Memory Group (Thomas Christophel) investigated the patterns of neuronal activity that enable the flexible modulation of our working memory. If you want to pick your brain a little check out their Journal of Cognitive Neuroscience Article!
Is your glass half full or half empty?
Research spanning various fields in psychology has consistently indicated that a person’s mental attitude influences the outcome several significant areas in one's future life. The Developmental and Educational Psychology Group (Denis Gerstorf) investigated how age, gender and education affects a the optimistic or pessimistic mindset of a person. Have a look at their Article in Psychology and Aging to find ou more!
2nd Insi(ght)de Seminar (2024)
- Matthias Ziegler (Psychology)
- Caren Tischendorf (Mathematics)
- Thomas Christophel (Psychology)
Guest Talk - Frederic Meunier
25-01-2024 (BCCN Lecture Hall, Philippstr. 13, Haus 6)
Frederic Meunier is a Professor at the Queensland Brain Institute in Brisbane, Australia.
He gave a fantastic talk on the 'Surprisingly dynamic "clustering" of synaptic vesicles at the nanoscale'.
Holy cow!
On request of the Federal Ministry of Food and Agriculture (Bundesministerium für Ernährung und Landwirtschaft) Gudrun Brockmann identified zootechnical markers for the improvement of breeding within the endangered German Black Pied cattle (Deutsches Schwarzbuntes Niederungsrind, DSN) breed for the particularly animal-friendly and sustainable production of animal products.
Unfortunately, the full Report is only available in German, but the abstract provides an informative summary. If you want to know more about this topic, check out Gudrun Brockmann's profile and additional information.
It's what's on the inside that counts!
Recent improvements in the field of single-cell and single-nucleus RNA-sequencing (scRNA-seq and snRNA-seq) technologies allow to monitor the expression of plant genes across cell types, upon treatments, in response to biotic and abiotic stresses, or between genotypes at an unprecedented resolution.
In this commentary, the Plant Cell and Molecular Biology Group (Kerstin Kaufmann) discusses common challenges associated with the use of single-cell transcriptomics in plants and propose general guidelines to improve reproducibility, quality, comparability, and interpretation, and to make the data readily available to the community in this fast-developing field of research. Check out their new Article in The Plant Cell!
What do learning and memory and our immune system have in common?
Non-coding RNAs (ncRNAs) form a diverse group of transcripts that, by definition, are not translated to produce proteins. For this reason, they were first classified as non-functional by-products or mis-products of transcription (or junk RNA). However, it became clear with time that ncRNAs act as important regulators that influence various biological functions in different cell types and tissues as they comprise transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as small RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, and also long ncRNAs.
In their Journal of Neurochemistry Review Marina Mikhaylova, together with Mason Musgrove and Timothy Bredy from the Queensland Brain Institute in Australia, portrayed groups of ncRNAs enriched in the brain that play a crucial role in the functional aspects of both learning and memory, as well as adaptive immunity, and reflect on how they might facilitate the exchange between these two evolutionarily old biological systems.
1st Insi(ght)de Seminar (2024)
12-01-2024 (Maud-Menten-Saal, Campus Nord)
- Andrew Plested (Biology)
- Mike Johannes (Oliver Benson Group - Physics)
Goodbye CRC 951...
In this physica status solidi (a) Guest Editorial Oliver Benson reviewed the scientific highlights from the final funding period of the Collaborative Research Center 951 (CRC 951) “Hybrid Inorganic/Organic Systems for Opto-Electronics (HIOS)”, which existed for the past twelve years. The CRC 951 connected researchers from Humboldt-Universität zu Berlin (coordinating university), Freie Universität zu Berlin, Technische Universität Berlin, Universität Potsdam, the Fritz-Haber-Institut der Max-Planck-Gesellschaft, as well as the Helmholtz-Zentrum Berlin für Materialien und Energie GmbH.
Mind your own mood!
The Psychological Assessment Group (Matthias Ziegler) investigated how mindfulness affected the mood in response to a mobile-app-supported, mindfulness-based intervention. If you are curious whether mindfullness can improve the mood, have a look at their Article released by Applied Psychology: Health and Well‐Being!
Dream well, little horse...
Lorenz Gygax from the Animal Husbandry and Ethology Group investigated how changes in the social and spatial environment of horses throughout the day influence their recumbency (lying down) periods, which affect their REM sleep. To see what helps horses to dream check out their Article published in Equine Vetenary Journal!