Spatio-temporal dynamics at genomic level

Techniques developed in modern organic chemistry and statistical physics are needed to describe diffusion processes and to detect macromolecules in three-dimensional living systems. The Bioorganic Synthesis Group (Oliver Seitz) has generated tailor-made organic probes, which have been used in collaboration with groups from the Department of Biology to localize RNAs in living tissues, including the Molecular Genetics Group (Christian Schmitz-Linnewber).

The 3D genome organization and spatio-temporal gene expression can only be measured since very recently. Groups that are interested in 3D genome organization for life stock breeding purposes, such as the Breeding Biology and Molecular Genetics Group (Gudrun Brockmann) could benefit from the epigenetic expertise available in the Plant Cell and Molecular Biology (Kerstin Kaufmann) and Molecular Cell Biology (Ann Ehrenhofer-Murray) Groups.